A rocket startup's big Florida launch debut ended with all four mini satellites destroyed Thursday.

California-based Astra sent its rocket soaring from Cape Canaveral after multiple delays, including a last-second engine shutdown Monday. The 43-foot (13-meter) rocket arced through a clear afternoon sky out over the Atlantic, carrying small research satellites sponsored by NASA.

But shortly after the first-stage booster dropped away, onboard cameras showed the second stage igniting and appearing to tumble. The video cameras went dark less than four minutes into the flight and the airwaves grew silent.

A launch commentator finally confirmed that the payloads failed to reach orbit. Three of the CubeSats were built by universities in Alabama, New Mexico and California, while the fourth was from NASA's Johnson Space Center in Houston. All ended up crashing into the ocean.

Astra CEO and founder Chris Kemp apologized for the loss in a tweet: "I'm with the team looking at data, and we will provide more info as soon as we can."

NASA mission manager Hamilton Fernandez reiterated the space agency's support following the accident.

"Missions like these are critical for developing new launch vehicles in this growing commercial sector," Fernandez said in a statement.