Matthias will be launched alongside NASA astronauts Raja Chari, Tom Marshburn and Kayla Barron. Collectively known as Crew-3, the four astronauts will travel aboard the SpaceX Crew Dragon spacecraft Endurance and dock to the Space Station around 22 hours after liftoff.

During the journey to and from the Space Station, Matthias and Kayla will be mission specialists, working with spacecraft commander Raja and pilot Tom to monitor the spacecraft during the dynamic launch and re-entry phases of flight.